http://elementscommunity.org/forum/level-3-anvil/biotoxin-biotoxin/ Instead of "Max 1 per creature per turn", it can be "Target a non-poisoned creature you own. It and foe get poisoned equal to the creature's cost"
Basic effect: Poison at the cost of your creature.
If the creature has more cost than HP (most dragons) it just replaces your creature's attack for sticky damage.
If the creature has more HP than cost it may gain tummy advantages (flying Titan, Voodoo + Adrenaline, Tesserract + expensive stuff...)
Alternative 2: "Sacrifice a creature. Foe gets poisoned equal to the creature's cost." This gets dangerous with Phoenixes only, I guess.